GöTTINGEN, Germany -- In 1990, the scientists Jon Wolff and colleagues at the University of Wisconsin were the first to show that naked plasmid DNA could be taken up and expressed by muscle cells in vivo. Understanding and perfecting gene delivery to cells in culture has been the goal since before the beginning of Mirus. In 1996, Mirus scientists introduced TransIT LT-1, a breakthrough transfection reagent that was the first to combine high efficiency delivery with low toxicity (LT-1) to cells. This reagent remains a transfection reagent of choice for many researchers to this day.
TransIT-X2® for Transfection of DNA and siRNA into Multiple Cell Types
For optimal delivery of either DNA or siRNA into a variety of cell types, Mirus offers the TransIT-X2® Dynamic Delivery System. This novel formulation relies on a nonliposomal, polymeric chemistry system for efficient delivery of nucleic acids through cellular endosomal processes. The TransIT-X2® Dynamic Delivery System provides multiple advantages over outdated liposomal methods, including better DNA delivery, more efficient delivery of siRNA, and less toxicity across multiple cell types.
Experience the transfection breakthrough and achieve superior transfections with an innovative polymeric system. The TransIT-X2® Dynamic Delivery System gives researchers:
Efficiency – Exceptional Broad Spectrum Transfection
Versatility – Cutting Edge Delivery of Plasmid DNA and siRNA
Technology – Novel, Non-Liposomal, Polymeric Delivery
MoBiTec offers TransIT-X2® to its customer in Germany and some adjacent countries. Please check the link below for further details.
http://www.mobitec.com/cms/products/bio/06_cell_bio/trans...
MoBiTec GmbH (Goettingen, Germany) is a privately held company (founded in 1987) that offers research tools for molecular and cell biology. Products include DNA vectors for cloning and expression, cell transfection reagents and cell culture tools, immobilized and soluble enzymes, products for genomics and proteomics research, numerous antibodies and recombinant proteins, superior fluorescence reagents and kits, affinity chromatography products, as well as general laboratory equipment.
In parallel to its own product lines, MoBiTec distributes products from international companies in Germany. MoBiTec products are distributed worldwide, in Germany from their home office, in other countries by distributors.
'Lipofectamine is a trademark of Life Technologies Corporation'
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MoBiTec GmbH