The concept of targeted protein degradation presents revolutionary drug development opportunities and is anticipated to bring about a paradigm shift in modern healthcare. The first targeted protein degrader, called proteolysis targeting chimera (PROTAC), was developed about a decade ago. Presently, a variety of other such chemical entities and molecular glues are under investigation. In fact, certain pipeline candidates are already in the mid to late-phase trials and are anticipated to soon enter the market.
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The USD 3.6 billion (by 2030) financial opportunity within the target protein degradation market has been analyzed across the following segments:
Type of payment of licensing agreements
Upfront payments
Milestone payments
Type of protein degrader
Degronimids
PROTACs
SARDs / SERDs
Specific BET and DUB inhibitors
Other protein degraders
Therapeutic area
Neurodegenerative disorders
Oncological disorders
Other therapeutic areas
Route of administration
Oral
Intravenous
Other routes
Key geographical region
North America
Europe
Asia-Pacific
The Targeted Protein Degradation Market: Focus on Therapeutics and Technology Platforms (based on Degronimids, ENDTACs, Epichaperome Inhibitors, Hydrophobic Tags, IMiDs, LYTACs, Molecular Glues, PHOTACs, PROTACs, Protein Homeostatic Modulators, SARDs, SERDs, SNIPERs, and Specific BET and DUB Inhibitors), 2020-2030 report features the following companies, which we identified to be key players in this domain:
Arvinas
Captor Therapeutics
Celgene
Genetech
Kymera Therapeutics
Mission Therapeutics
Progenra
Radius Health
Sanofi Genzyme
Zenopharm
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Current Market Landscape
5. Company Profiles
6. Clinical Trial Analysis
7. KOL Analysis
8. Publication Analysis
9. Funding and Investment Analysis
10. Partnerships and Collaborations
11. Market Sizing and Opportunity Analysis
12. Executive Insights
13. Concluding Remarks
14. Appendix 1: Tabulated Data
15. Appendix 2: List of Companies and Organizations
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